Know which stops allow crew, and stay in the zone
The runner manual spells out which aid stations are crew-accessible, where you can park, and where you can set up. Hand your runner food, drinks, or gear outside a designated crew area and it is often an automatic disqualification, so never meet them at some random road crossing unless the rules say you can. Mark the crew-allowed stations on your sheet and treat everywhere else as hands-off.
A lot of races also gate pacers, who often cannot join until the halfway point or a set distance like mile 50 or mile 60. Sort out the pacer rules early so nobody is standing at the wrong aid station expecting to run.