Pritchett Peak sets the tone
The 100K starts in the dark with a hard climb up Pritchett Peak, and you get a sunrise summit before the day really gets going. It is the single biggest sustained climb on the whole course, and it comes while your legs are still fresh, and that is the trap. It feels easy to push here. Pushing here is how people pay for it later, on a course that never gives your legs a real break.
So climb the opener by effort. Hike the steep stuff with purpose and save your running legs for the rolling singletrack that comes after. There is a second decent climb up toward the South Lake trailhead before the long middle of the race settles into that rhythm of constant ups and downs.