Lift for strength, not for a burn
The point of strength work for an ultra runner is durable force and tissue that does not break down, not size and not a gym pump. So you lift fairly heavy, in the 4 to 8 rep range, you rest fully between sets, and you put good form ahead of chasing fatigue. You are training your legs, tendons, and stabilizers to soak up thousands of loaded foot strikes, especially on the downhills, without falling apart.
And honestly, most of the benefit comes from just being consistent, not from heroics. Two real sessions every week for months will beat four sessions for three weeks and then nothing. Treat strength as a permanent part of your training, not a phase you finish and move on from.