Run long on tired legs, on purpose
The point of a back-to-back is not the single distance, it is the second day. Going out long again on already-trashed legs is the closest you can get to rehearsing what mile 120 onward actually feels like, and it trains your legs, your gut, and your head to keep moving forward when none of them want to. A classic pattern is a longer, more honest effort on Saturday, then a Sunday that is all about forward motion: easier, more power-hiking, no hero pace.
Schedule the big blocks every two to three weeks, not every weekend, because they take real recovery to bounce back from. As you move into your peak, stretch one or two of them into three-day blocks so you spend a whole weekend accumulating fatigue. And do them like the race: on terrain with similar vert, in your actual pack, eating your actual race food, ideally with one of them running into the dark.