The climbs: steep, and there is more than one
This is not a course with one crux climb and easy running around it. The 25K has three major climbs, the 50K has five, and all of them are steep and sustained rather than gradual. Hike the steep pitches with purpose from the first climb, because the terrain does not let up enough later in the day to make up time you lost being conservative early.
The Hyner View overlook itself sits at mile 4 on both distances and is the payoff for the first big climb, a real vista worth the effort. But do not let the view slow you down here: this is also your first hard cutoff.