The loop: relentless, technical, no rhythm to settle into
Forget elevation profiles here. There is no signature climb to brace for, just constant short, steep, punchy ups and downs over roots and rock, lap after lap. The named grinders are Sasquatch Summit around mile 7.4 of each loop, with more climbing waiting near miles 8 and 16, and the late-loop climbs runners call the Soul Crusher and Hallucination Hill because they get meaner every time you come back to them. The toughest northern stretch dumps you out at Kelly’s Kitchen around mile 11.7, which is exactly why that aid station is there.
The thing that wears people down is that you almost never get to settle into a rhythm. The trail is technical enough that you are picking your feet up the whole time, and the climbs are too short to power-hike comfortably but too steep to run cheaply. Patience is the skill. Run the loop like you have to do it five times, because you do, and the runners who hold something back early are the ones still moving well at 2 AM.