The early miles: climb, then a long descent that costs you
You start at 5:30 in the dark and head uphill, so settle in and treat the first climb as a warm-up, not a place to make a statement. Then comes a long descent, and this is the first trap of the day. Bombing the early downhill feels great and free, but it quietly trashes your quads, and you still have hours of climbing and the Apple Orchard Falls grind ahead of you. Run the descents controlled and you arrive at the hard part with legs that still work.
A chunk of the early course runs on forest-service and dirt road plus some soft grassy road up near the high country, so the footing is friendlier here than it is later. Use the runnable sections to move efficiently and eat, because the technical stuff and the big climb are coming.