The first half: bank patience, not time
The early miles feel great. Fresh legs, daylight, runnable trail in places, and the kind of scenery that makes you want to push. Do not. The single best decision you make all day is running the first 40 or 50 miles easier than feels right, because the technical footing keeps taxing your legs whether you notice it or not. Hike the short climbs out of the drainages, keep your effort flat, and get to the back half with quads that still work.
Aid is reasonably spaced for a remote hundred, with around 14 manned on-course stations, but the gaps still get long out there. The longest stretch runs about 7.6 miles between No Business and Duncan Hollow, so leave each aid with enough food and fluid to cover the next leg and then some. Out here, assuming the next aid is close is how people end up walking it in on empty.